Aetiology, comorbidities and cofactors of chronic leg ulcers: retrospective evaluation of 1 000 patients from 10 specialised dermatological wound care centers in Germany.
Identifieur interne : 001446 ( Main/Exploration ); précédent : 001445; suivant : 001447Aetiology, comorbidities and cofactors of chronic leg ulcers: retrospective evaluation of 1 000 patients from 10 specialised dermatological wound care centers in Germany.
Auteurs : Finja Jockenhöfer [Allemagne] ; Harald Gollnick [Allemagne] ; Katharina Herberger [Allemagne] ; Georg Isbary [Allemagne] ; Regina Renner [Allemagne] ; Markus Stücker [Allemagne] ; Eva Valesky [Allemagne] ; Uwe Wollina [Allemagne] ; Michael Weichenthal [Allemagne] ; Sigrid Karrer [Allemagne] ; Bernhard Kuepper [Nouvelle-Zélande] ; Alexander Roesch [Allemagne] ; Joachim Dissemond [Allemagne]Source :
- International wound journal [ 1742-481X ] ; 2016.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Allemagne (épidémiologie), Centres de traumatologie (), Comorbidité, Enfant, Facteurs de risque, Femelle, Humains, Jeune adulte, Maladie chronique, Mâle, Services de consultations externes des hôpitaux (), Sujet âgé, Sujet âgé de 80 ans ou plus, Ulcère de la jambe (épidémiologie), Ulcère de la jambe (étiologie), Études rétrospectives.
- MESH :
- épidémiologie : Allemagne, Ulcère de la jambe.
- étiologie : Ulcère de la jambe.
- Adolescent, Adulte, Adulte d'âge moyen, Centres de traumatologie, Comorbidité, Enfant, Facteurs de risque, Femelle, Humains, Jeune adulte, Maladie chronique, Mâle, Services de consultations externes des hôpitaux, Sujet âgé, Sujet âgé de 80 ans ou plus, Études rétrospectives.
English descriptors
- KwdEn :
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Chronic Disease, Comorbidity, Female, Germany (epidemiology), Humans, Leg Ulcer (epidemiology), Leg Ulcer (etiology), Male, Middle Aged, Outpatient Clinics, Hospital (statistics & numerical data), Retrospective Studies, Risk Factors, Trauma Centers (statistics & numerical data), Young Adult.
- MESH :
- epidemiology : Germany, Leg Ulcer.
- etiology : Leg Ulcer.
- statistics & numerical data : Outpatient Clinics, Hospital, Trauma Centers.
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Chronic Disease, Comorbidity, Female, Humans, Male, Middle Aged, Retrospective Studies, Risk Factors, Young Adult.
Abstract
Numerous comorbidities and cofactors have been known to influence wound healing processes. In this multicentre study, clinical data of 1 000 patients with chronic leg ulcers from ten specialised dermatological wound care centers were analysed. The patient cohort comprised 567 females and 433 males with an average age of 69·9 years. The wounds persisted on average for 40·8 months and had a mean size of 43·7 cm(2) . Venous leg ulcers represented the most common entity accounting for 51·3% of all chronic wounds, followed by mixed-type ulcers in 12·9% and arterial ulcerations in 11·0% of the patients. Vasculitis was diagnosed in 4·5%, trauma in 3·2%, pyoderma gangrenosum in 2·8%, lymphoedema in 1·7%, neoplasia in 1·0% and delayed post-surgical wound healing in 0·6% of the included patients. In total, 70·5% of patients suffered from arterial hypertension, 45·2% were obese, 27·2% had non-insulin dependent diabetes, and 24·4% dyslipidaemia. Altogether 18·4% suffered from metabolic syndrome. Cofactors and comorbidities of patients with chronic leg ulcers have previously been studied but not in detail. Here, we were able to demonstrate the existence of several potentially relevant cofactors, comorbidities of their associations and geographical distributions, which should be routinely examined in patients with chronic leg ulcers and - if possible - treated.
DOI: 10.1111/iwj.12387
PubMed: 25483380
Affiliations:
- Allemagne, Nouvelle-Zélande
- Bavière, District de Darmstadt, District de Dresde, District de Haute-Bavière, District de Moyenne-Franconie, Hambourg, Hesse (Land), Saxe (Land), Saxe-Anhalt
- Dresde, Erlangen, Francfort-sur-le-Main, Hambourg, Magdebourg, Munich
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 001151
- to stream PubMed, to step Curation: 001151
- to stream PubMed, to step Checkpoint: 001151
- to stream Ncbi, to step Merge: 006E16
- to stream Ncbi, to step Curation: 006E16
- to stream Ncbi, to step Checkpoint: 006E16
- to stream Main, to step Merge: 001448
- to stream Main, to step Curation: 001446
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Aetiology, comorbidities and cofactors of chronic leg ulcers: retrospective evaluation of 1 000 patients from 10 specialised dermatological wound care centers in Germany.</title><author><name sortKey="Jockenhofer, Finja" sort="Jockenhofer, Finja" uniqKey="Jockenhofer F" first="Finja" last="Jockenhöfer">Finja Jockenhöfer</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Venereology and Allergology, University Hospital of Essen, Essen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology, Venereology and Allergology, University Hospital of Essen, Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Gollnick, Harald" sort="Gollnick, Harald" uniqKey="Gollnick H" first="Harald" last="Gollnick">Harald Gollnick</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology and Venereology, University Hospital of Magdeburg, Magdeburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology and Venereology, University Hospital of Magdeburg, Magdeburg</wicri:regionArea><placeName><region type="land" nuts="2">Saxe-Anhalt</region><settlement type="city">Magdebourg</settlement></placeName></affiliation></author><author><name sortKey="Herberger, Katharina" sort="Herberger, Katharina" uniqKey="Herberger K" first="Katharina" last="Herberger">Katharina Herberger</name><affiliation wicri:level="3"><nlm:affiliation>Institute for Healthcare Research of Dermatology and Health Care Professions, University Hospital of Hamburg, Hamburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Healthcare Research of Dermatology and Health Care Professions, University Hospital of Hamburg, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation></author><author><name sortKey="Isbary, Georg" sort="Isbary, Georg" uniqKey="Isbary G" first="Georg" last="Isbary">Georg Isbary</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology, Allergology and Environment Medicine, Clinical Centre Schwabing Munich, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology, Allergology and Environment Medicine, Clinical Centre Schwabing Munich, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation></author><author><name sortKey="Renner, Regina" sort="Renner, Regina" uniqKey="Renner R" first="Regina" last="Renner">Regina Renner</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology and Venereology, University Hospital of Erlangen, Erlangen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology and Venereology, University Hospital of Erlangen, Erlangen</wicri:regionArea><placeName><settlement type="city">Erlangen</settlement><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Moyenne-Franconie</region></placeName></affiliation></author><author><name sortKey="Stucker, Markus" sort="Stucker, Markus" uniqKey="Stucker M" first="Markus" last="Stücker">Markus Stücker</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Centre for venous disease of the dermatological and vascular surgery, University Hospital of Bochum, Bochum, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology, Centre for venous disease of the dermatological and vascular surgery, University Hospital of Bochum, Bochum</wicri:regionArea><wicri:noRegion>Bochum</wicri:noRegion><wicri:noRegion>Bochum</wicri:noRegion><wicri:noRegion>Bochum</wicri:noRegion></affiliation></author><author><name sortKey="Valesky, Eva" sort="Valesky, Eva" uniqKey="Valesky E" first="Eva" last="Valesky">Eva Valesky</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology and Venereology, University Hospital of Frankfurt a. M., Frankfurt, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology and Venereology, University Hospital of Frankfurt a. M., Frankfurt</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Darmstadt</region><settlement type="city">Francfort-sur-le-Main</settlement></placeName></affiliation></author><author><name sortKey="Wollina, Uwe" sort="Wollina, Uwe" uniqKey="Wollina U" first="Uwe" last="Wollina">Uwe Wollina</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology, Venereology and Allergology, Hospital Dresden-Friedrichstadt, Dresden, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology, Venereology and Allergology, Hospital Dresden-Friedrichstadt, Dresden</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Dresde</region><settlement type="city">Dresde</settlement></placeName></affiliation></author><author><name sortKey="Weichenthal, Michael" sort="Weichenthal, Michael" uniqKey="Weichenthal M" first="Michael" last="Weichenthal">Michael Weichenthal</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Venereology, University Hospital of Kiel, Keil, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology, Venereology, University Hospital of Kiel, Keil</wicri:regionArea><wicri:noRegion>Keil</wicri:noRegion><wicri:noRegion>Keil</wicri:noRegion><wicri:noRegion>Keil</wicri:noRegion></affiliation></author><author><name sortKey="Karrer, Sigrid" sort="Karrer, Sigrid" uniqKey="Karrer S" first="Sigrid" last="Karrer">Sigrid Karrer</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Venereology, University Hospital of Regensburg, Regensburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology, Venereology, University Hospital of Regensburg, Regensburg</wicri:regionArea><wicri:noRegion>Regensburg</wicri:noRegion><wicri:noRegion>Regensburg</wicri:noRegion><wicri:noRegion>Regensburg</wicri:noRegion></affiliation></author><author><name sortKey="Kuepper, Bernhard" sort="Kuepper, Bernhard" uniqKey="Kuepper B" first="Bernhard" last="Kuepper">Bernhard Kuepper</name><affiliation wicri:level="1"><nlm:affiliation>General Medical Department, Timaru Public Hospital, SCDHB, Timaru, New Zealand.</nlm:affiliation><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea>General Medical Department, Timaru Public Hospital, SCDHB, Timaru</wicri:regionArea><wicri:noRegion>Timaru</wicri:noRegion></affiliation></author><author><name sortKey="Roesch, Alexander" sort="Roesch, Alexander" uniqKey="Roesch A" first="Alexander" last="Roesch">Alexander Roesch</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Venereology and Allergology, University Hospital of Essen, Essen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology, Venereology and Allergology, University Hospital of Essen, Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Dissemond, Joachim" sort="Dissemond, Joachim" uniqKey="Dissemond J" first="Joachim" last="Dissemond">Joachim Dissemond</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Venereology and Allergology, University Hospital of Essen, Essen, Germany. joachim.dissemond@uk-essen.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology, Venereology and Allergology, University Hospital of Essen, Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2016">2016</date><idno type="RBID">pubmed:25483380</idno><idno type="pmid">25483380</idno><idno type="doi">10.1111/iwj.12387</idno><idno type="wicri:Area/PubMed/Corpus">001151</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001151</idno><idno type="wicri:Area/PubMed/Curation">001151</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001151</idno><idno type="wicri:Area/PubMed/Checkpoint">001151</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001151</idno><idno type="wicri:Area/Ncbi/Merge">006E16</idno><idno type="wicri:Area/Ncbi/Curation">006E16</idno><idno type="wicri:Area/Ncbi/Checkpoint">006E16</idno><idno type="wicri:Area/Main/Merge">001448</idno><idno type="wicri:Area/Main/Curation">001446</idno><idno type="wicri:Area/Main/Exploration">001446</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Aetiology, comorbidities and cofactors of chronic leg ulcers: retrospective evaluation of 1 000 patients from 10 specialised dermatological wound care centers in Germany.</title><author><name sortKey="Jockenhofer, Finja" sort="Jockenhofer, Finja" uniqKey="Jockenhofer F" first="Finja" last="Jockenhöfer">Finja Jockenhöfer</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Venereology and Allergology, University Hospital of Essen, Essen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology, Venereology and Allergology, University Hospital of Essen, Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Gollnick, Harald" sort="Gollnick, Harald" uniqKey="Gollnick H" first="Harald" last="Gollnick">Harald Gollnick</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology and Venereology, University Hospital of Magdeburg, Magdeburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology and Venereology, University Hospital of Magdeburg, Magdeburg</wicri:regionArea><placeName><region type="land" nuts="2">Saxe-Anhalt</region><settlement type="city">Magdebourg</settlement></placeName></affiliation></author><author><name sortKey="Herberger, Katharina" sort="Herberger, Katharina" uniqKey="Herberger K" first="Katharina" last="Herberger">Katharina Herberger</name><affiliation wicri:level="3"><nlm:affiliation>Institute for Healthcare Research of Dermatology and Health Care Professions, University Hospital of Hamburg, Hamburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Healthcare Research of Dermatology and Health Care Professions, University Hospital of Hamburg, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation></author><author><name sortKey="Isbary, Georg" sort="Isbary, Georg" uniqKey="Isbary G" first="Georg" last="Isbary">Georg Isbary</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology, Allergology and Environment Medicine, Clinical Centre Schwabing Munich, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology, Allergology and Environment Medicine, Clinical Centre Schwabing Munich, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation></author><author><name sortKey="Renner, Regina" sort="Renner, Regina" uniqKey="Renner R" first="Regina" last="Renner">Regina Renner</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology and Venereology, University Hospital of Erlangen, Erlangen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology and Venereology, University Hospital of Erlangen, Erlangen</wicri:regionArea><placeName><settlement type="city">Erlangen</settlement><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Moyenne-Franconie</region></placeName></affiliation></author><author><name sortKey="Stucker, Markus" sort="Stucker, Markus" uniqKey="Stucker M" first="Markus" last="Stücker">Markus Stücker</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Centre for venous disease of the dermatological and vascular surgery, University Hospital of Bochum, Bochum, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology, Centre for venous disease of the dermatological and vascular surgery, University Hospital of Bochum, Bochum</wicri:regionArea><wicri:noRegion>Bochum</wicri:noRegion><wicri:noRegion>Bochum</wicri:noRegion><wicri:noRegion>Bochum</wicri:noRegion></affiliation></author><author><name sortKey="Valesky, Eva" sort="Valesky, Eva" uniqKey="Valesky E" first="Eva" last="Valesky">Eva Valesky</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology and Venereology, University Hospital of Frankfurt a. M., Frankfurt, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology and Venereology, University Hospital of Frankfurt a. M., Frankfurt</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Darmstadt</region><settlement type="city">Francfort-sur-le-Main</settlement></placeName></affiliation></author><author><name sortKey="Wollina, Uwe" sort="Wollina, Uwe" uniqKey="Wollina U" first="Uwe" last="Wollina">Uwe Wollina</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology, Venereology and Allergology, Hospital Dresden-Friedrichstadt, Dresden, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology, Venereology and Allergology, Hospital Dresden-Friedrichstadt, Dresden</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Dresde</region><settlement type="city">Dresde</settlement></placeName></affiliation></author><author><name sortKey="Weichenthal, Michael" sort="Weichenthal, Michael" uniqKey="Weichenthal M" first="Michael" last="Weichenthal">Michael Weichenthal</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Venereology, University Hospital of Kiel, Keil, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology, Venereology, University Hospital of Kiel, Keil</wicri:regionArea><wicri:noRegion>Keil</wicri:noRegion><wicri:noRegion>Keil</wicri:noRegion><wicri:noRegion>Keil</wicri:noRegion></affiliation></author><author><name sortKey="Karrer, Sigrid" sort="Karrer, Sigrid" uniqKey="Karrer S" first="Sigrid" last="Karrer">Sigrid Karrer</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Venereology, University Hospital of Regensburg, Regensburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology, Venereology, University Hospital of Regensburg, Regensburg</wicri:regionArea><wicri:noRegion>Regensburg</wicri:noRegion><wicri:noRegion>Regensburg</wicri:noRegion><wicri:noRegion>Regensburg</wicri:noRegion></affiliation></author><author><name sortKey="Kuepper, Bernhard" sort="Kuepper, Bernhard" uniqKey="Kuepper B" first="Bernhard" last="Kuepper">Bernhard Kuepper</name><affiliation wicri:level="1"><nlm:affiliation>General Medical Department, Timaru Public Hospital, SCDHB, Timaru, New Zealand.</nlm:affiliation><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea>General Medical Department, Timaru Public Hospital, SCDHB, Timaru</wicri:regionArea><wicri:noRegion>Timaru</wicri:noRegion></affiliation></author><author><name sortKey="Roesch, Alexander" sort="Roesch, Alexander" uniqKey="Roesch A" first="Alexander" last="Roesch">Alexander Roesch</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Venereology and Allergology, University Hospital of Essen, Essen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology, Venereology and Allergology, University Hospital of Essen, Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Dissemond, Joachim" sort="Dissemond, Joachim" uniqKey="Dissemond J" first="Joachim" last="Dissemond">Joachim Dissemond</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Venereology and Allergology, University Hospital of Essen, Essen, Germany. joachim.dissemond@uk-essen.de.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology, Venereology and Allergology, University Hospital of Essen, Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author></analytic><series><title level="j">International wound journal</title><idno type="eISSN">1742-481X</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Child</term><term>Chronic Disease</term><term>Comorbidity</term><term>Female</term><term>Germany (epidemiology)</term><term>Humans</term><term>Leg Ulcer (epidemiology)</term><term>Leg Ulcer (etiology)</term><term>Male</term><term>Middle Aged</term><term>Outpatient Clinics, Hospital (statistics & numerical data)</term><term>Retrospective Studies</term><term>Risk Factors</term><term>Trauma Centers (statistics & numerical data)</term><term>Young Adult</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Allemagne (épidémiologie)</term><term>Centres de traumatologie ()</term><term>Comorbidité</term><term>Enfant</term><term>Facteurs de risque</term><term>Femelle</term><term>Humains</term><term>Jeune adulte</term><term>Maladie chronique</term><term>Mâle</term><term>Services de consultations externes des hôpitaux ()</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Ulcère de la jambe (épidémiologie)</term><term>Ulcère de la jambe (étiologie)</term><term>Études rétrospectives</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Germany</term><term>Leg Ulcer</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Leg Ulcer</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Outpatient Clinics, Hospital</term><term>Trauma Centers</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Allemagne</term><term>Ulcère de la jambe</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Ulcère de la jambe</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Child</term><term>Chronic Disease</term><term>Comorbidity</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Retrospective Studies</term><term>Risk Factors</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Centres de traumatologie</term><term>Comorbidité</term><term>Enfant</term><term>Facteurs de risque</term><term>Femelle</term><term>Humains</term><term>Jeune adulte</term><term>Maladie chronique</term><term>Mâle</term><term>Services de consultations externes des hôpitaux</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Études rétrospectives</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Numerous comorbidities and cofactors have been known to influence wound healing processes. In this multicentre study, clinical data of 1 000 patients with chronic leg ulcers from ten specialised dermatological wound care centers were analysed. The patient cohort comprised 567 females and 433 males with an average age of 69·9 years. The wounds persisted on average for 40·8 months and had a mean size of 43·7 cm(2) . Venous leg ulcers represented the most common entity accounting for 51·3% of all chronic wounds, followed by mixed-type ulcers in 12·9% and arterial ulcerations in 11·0% of the patients. Vasculitis was diagnosed in 4·5%, trauma in 3·2%, pyoderma gangrenosum in 2·8%, lymphoedema in 1·7%, neoplasia in 1·0% and delayed post-surgical wound healing in 0·6% of the included patients. In total, 70·5% of patients suffered from arterial hypertension, 45·2% were obese, 27·2% had non-insulin dependent diabetes, and 24·4% dyslipidaemia. Altogether 18·4% suffered from metabolic syndrome. Cofactors and comorbidities of patients with chronic leg ulcers have previously been studied but not in detail. Here, we were able to demonstrate the existence of several potentially relevant cofactors, comorbidities of their associations and geographical distributions, which should be routinely examined in patients with chronic leg ulcers and - if possible - treated.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Nouvelle-Zélande</li></country><region><li>Bavière</li><li>District de Darmstadt</li><li>District de Dresde</li><li>District de Haute-Bavière</li><li>District de Moyenne-Franconie</li><li>Hambourg</li><li>Hesse (Land)</li><li>Saxe (Land)</li><li>Saxe-Anhalt</li></region><settlement><li>Dresde</li><li>Erlangen</li><li>Francfort-sur-le-Main</li><li>Hambourg</li><li>Magdebourg</li><li>Munich</li></settlement></list><tree><country name="Allemagne"><noRegion><name sortKey="Jockenhofer, Finja" sort="Jockenhofer, Finja" uniqKey="Jockenhofer F" first="Finja" last="Jockenhöfer">Finja Jockenhöfer</name></noRegion><name sortKey="Dissemond, Joachim" sort="Dissemond, Joachim" uniqKey="Dissemond J" first="Joachim" last="Dissemond">Joachim Dissemond</name><name sortKey="Gollnick, Harald" sort="Gollnick, Harald" uniqKey="Gollnick H" first="Harald" last="Gollnick">Harald Gollnick</name><name sortKey="Herberger, Katharina" sort="Herberger, Katharina" uniqKey="Herberger K" first="Katharina" last="Herberger">Katharina Herberger</name><name sortKey="Isbary, Georg" sort="Isbary, Georg" uniqKey="Isbary G" first="Georg" last="Isbary">Georg Isbary</name><name sortKey="Karrer, Sigrid" sort="Karrer, Sigrid" uniqKey="Karrer S" first="Sigrid" last="Karrer">Sigrid Karrer</name><name sortKey="Renner, Regina" sort="Renner, Regina" uniqKey="Renner R" first="Regina" last="Renner">Regina Renner</name><name sortKey="Roesch, Alexander" sort="Roesch, Alexander" uniqKey="Roesch A" first="Alexander" last="Roesch">Alexander Roesch</name><name sortKey="Stucker, Markus" sort="Stucker, Markus" uniqKey="Stucker M" first="Markus" last="Stücker">Markus Stücker</name><name sortKey="Valesky, Eva" sort="Valesky, Eva" uniqKey="Valesky E" first="Eva" last="Valesky">Eva Valesky</name><name sortKey="Weichenthal, Michael" sort="Weichenthal, Michael" uniqKey="Weichenthal M" first="Michael" last="Weichenthal">Michael Weichenthal</name><name sortKey="Wollina, Uwe" sort="Wollina, Uwe" uniqKey="Wollina U" first="Uwe" last="Wollina">Uwe Wollina</name></country><country name="Nouvelle-Zélande"><noRegion><name sortKey="Kuepper, Bernhard" sort="Kuepper, Bernhard" uniqKey="Kuepper B" first="Bernhard" last="Kuepper">Bernhard Kuepper</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001446 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001446 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:25483380
|texte= Aetiology, comorbidities and cofactors of chronic leg ulcers: retrospective evaluation of 1 000 patients from 10 specialised dermatological wound care centers in Germany.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:25483380" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |